Short answer: Not yet.
I am not a fan of bulk rimfire ammo of any kind, but I picked up a couple cartons when WMR was really hard to find. I pulled out my rim sorting tool, and found that it was just as uniform as any other CCI product, (which is very good). Shooting it in my assortment of .22 WMR rifles and handguns, it shoots to the same POI as the 50rd or 200rd. I'm guessing that the difference in cost is a matter of packaging and packing materials. You could dump a lot more ammo/unit time into the carton, there's no plastic "thingy" to mess with on a packaging line.
As to rim sorting, I sorted the carton ammo into the MTM 100 round flip top boxes. A nearly pointless task as it turns out, it all shoots the same. I've shot my way through about one carton, checking drop and group size with my handguns and rifles, 125yds with rifles, 15yds with my 2" LCRx, 50yds with my Single Six and Super Wrangler, (six total). No big number, but no issues to report. Fliers, minimal and few. No misfires, but my collection hasn't had a misfire with anything I've tried. The foxes were impressed, but not for long.
I wouldn't avoid a sale on "milk carton" CCI 22 WMR.