The 22LR will do the job, of course there is better choices, I have used 22LR for years, I just head shoot them, I now have a ruger 10/22 with a hogue stock and a BSA 4x32 scope with see through mounts, nice setup, had to use loctite I have found many years ago that Remington Yellow jackets work very well on Varmints, this is a hollow head bullet around 32 gr, really traveling, kinda on the pricey side around $24.00 bucks a brick in NH, note: Yellow jackets feed very well in my Rugers, Rugers seem to be picky with ammo. I also have the mark2 as well likes the yellow jacket's, also the Remington's burn very clean, lets say compared to Winchesters, now your talking dirty ammo I use a dry graphite to lube the bolt works well. Just my thoughts, remember shot placement is No# 1. Aim small hit small. RAMbo.