l6turbo did a post a while ago where he measured, I think, the 452 stocks? and showed negligible difference in the comb height even though they appear vastly different.
That said, I personally find a physical difference when using a hogback vs American stock. My experience is with 452's, but it's all very similar. I get really bad neck pain, so I know quite quickly when i'm in a forced position.
I find the hogback iron sights align perfectly when I shoulder the rifle, and thinking logically if that aligns perfectly, then a scope that sits a tad higher will be slightly out of alignment for me.
That said, with the measurements l6turbo did (and I can't quite remember the specifics) maybe for me, it's more to do with the butt plate placement and not the comb height, since if they are pretty much the same, I shouldn't get comfortable sight alignment on scoped American models which I do.
There's been a difference of opinion around here forever regarding chinweld, cheekweld etc. All I know is that I find a scoped hogback 452 a little out of alignment for myself and need to assume a chinweld, where normally my natural comfort position is a solid cheekweld, whilst iron sighted hogbacks are naturally comfortable and the american stocked with low mounted scopes fit me well.
I've put 42mm 1" scopes on a 452 lux before, and it works, but I have to adjust my behaviour as closing my eyes and shouldering the rifle to it's natural comfortable position for me always end up with my eye low when these designs are scoped. I also need to use a cheekriser of 1cm or so for cz527 carbines with .500" burris ring and 1" scopes, otherwise my eye line is low.